Abnormal liver blood tests are often detected incidentally in a health check or whilst investigating other conditions. The results might indicate underlying liver disease although some forms of serious liver disease such as cirrhosis can exist when the liver blood tests are normal. The cause of abnormal liver blood tests is best determined from a detailed medical history, taken by an experienced clinician alongside specific blood tests and scans. There are a large number of causes; some are common such as non-alcoholic fatty liver disease and heavy alcohol consumption, some are much rarer and require specific testing. The assessment of abnormal liver blood tests should always involve a liver scan to visualise the liver and exclude a liver lesion and then consideration of whether there is underlying liver disease and associated inflammation, scarring (fibrosis), bile duct damage or cirrhosis. A Fibroscan (LINK) can assist in determining whether there is significant fibrosis and/or fatty change.
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